Lime

Lime: moderate in histamine. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)Moderate
Lime behaves like lemon and arrives the same way - in a dressing, a marinade or a drink rather than as a fruit. It is a liberator, not a source. Where it differs is dose: a lime is smaller and more often used whole, zest included, and the zest is the most concentrated part. Citrus is on the elimination lists as a liberator, but the current review attributes its symptoms to its other amines — putrescine above all — competing for the enzyme that clears histamine.
Sources· 3
- Maintz & Novak, Am J Clin Nutr 2007
- Zuberbier et al., EAACI/GA2LEN urticaria guideline
- Comas-Basté O. et al., Biomolecules 10:1181 (2020), section 5.4.1, attributing the symptoms of citrus to its other amines, putrescine above all, competing for DAO
- TyramineNone
- SalicylateNone
- SucroseNone
- FODMAPsNone
- LactoseFODMAPsNone
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- FructoseFODMAPsNone
- NickelNone
- OxalatesNone
- GlutenNone
Intolerance levels are based on our documented scientific sources. See sources →
React to Histamine (+liberators / DAO inhibitors)? Check these too
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Frequently asked questions
Which intolerances does lime affect?
Lime is notable for histamine. Clear on tyramine, salicylate, sucrose, FODMAPs, lactose, oligosaccharides, sorbitol, fructose, nickel, oxalates and gluten.
Does lime contain histamine?
Lime contains moderate levels of histamine. Lime behaves like lemon and arrives the same way - in a dressing, a marinade or a drink rather than as a fruit. It is a liberator, not a source. Where it differs is dose: a lime is smaller and more often used whole, zest included, and the zest is the most concentrated part. Citrus is on the elimination lists as a liberator, but the current review attributes its symptoms to its other amines — putrescine above all — competing for the enzyme that clears histamine. Amounts vary by brand and recipe, so always check the label of the exact product.
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