Azorubine

Azorubine is notable for salicylate and histamine. Clear on tyramine, sucrose, FODMAPs, lactose, oligosaccharides, sorbitol, fructose, nickel, oxalates and gluten.

Yes — azorubine is high in salicylate. Azorubine is an azo dye used for reds and berry shades, and one of the colours grouped with tartrazine as a salicylate cross-reactor. It is also one of the six colours of Annex V of the additives regulation, which must carry the children's attention warning on the label - a different endpoint from this axis: attention, not salicylate.

Azorubine contains moderate levels of histamine. Azorubine (E122, also sold as carmoisine) colours the reds and berry shades of sweets, jellies and packet cakes. Another of the Southampton six, so it carries the children's attention warning. The dye holds no histamine of its own, so whatever it does is not a question of content - but release is the elimination protocols' classification of it, not a demonstrated mechanism. The Swiss list rates it 2 of 3 and marks it L, its letter for liberators of mast cell mediators — a presumed reason rather than a measurement. Amounts vary by brand and recipe, so always check the label of the exact product.