Lemon

Lemon: moderate in histamine; low in salicylate. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)Moderate
Lemon is one of the citrus fruits the elimination lists name, and it is a liberator rather than a source - it holds almost no histamine itself. The practical problem is that lemon is not a food you decide to eat: it is squeezed over fish, into dressings and into tea, so it arrives without being counted. Citrus is on the elimination lists as a liberator, but the current review attributes its symptoms to its other amines — putrescine above all — competing for the enzyme that clears histamine.
Sources· 4
- Maintz & Novak, Am J Clin Nutr 2007
- Zuberbier et al., EAACI/GA2LEN urticaria guideline
- SIGHI food-compatibility list
- Comas-Basté O. et al., Biomolecules 10:1181 (2020), section 5.4.1, attributing the symptoms of citrus to its other amines, putrescine above all, competing for DAO
- SalicylateLow
Lemon measures 6.7 mg of salicylate per kilogram, and the serve the survey used was 6 g - a squeeze - which delivers 0.04 mg, the smallest per-serve figure of any fruit measured. That gap is the whole argument of the paper: a food can be middling per kilogram and negligible in practice because nobody eats a kilogram of it. The zest is the part to watch, being skin.
Sources· 1
- Malakar S, Gibson PR, Barrett JS & Muir JG, J Food Compos Anal 57 (2017), 31-39 - salicylic acid measured by GC-MS in 112 common foods, reported per serve as well as per kilogram
- TyramineNone
- SucroseNone
- FODMAPsNone
- LactoseFODMAPsNone
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- FructoseFODMAPsNone
- NickelNone
- OxalatesNone
- GlutenNone
Intolerance levels are based on our documented scientific sources. See sources →
React to Histamine (+liberators / DAO inhibitors)? Check these too
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Frequently asked questions
Which intolerances does lemon affect?
Lemon is notable for histamine and salicylate. Clear on tyramine, sucrose, FODMAPs, lactose, oligosaccharides, sorbitol, fructose, nickel, oxalates and gluten.
Does lemon contain histamine?
Lemon contains moderate levels of histamine. Lemon is one of the citrus fruits the elimination lists name, and it is a liberator rather than a source - it holds almost no histamine itself. The practical problem is that lemon is not a food you decide to eat: it is squeezed over fish, into dressings and into tea, so it arrives without being counted. Citrus is on the elimination lists as a liberator, but the current review attributes its symptoms to its other amines — putrescine above all — competing for the enzyme that clears histamine.
Does lemon contain salicylate?
Lemon contains only low levels of salicylate. Lemon measures 6.7 mg of salicylate per kilogram, and the serve the survey used was 6 g - a squeeze - which delivers 0.04 mg, the smallest per-serve figure of any fruit measured. That gap is the whole argument of the paper: a food can be middling per kilogram and negligible in practice because nobody eats a kilogram of it. The zest is the part to watch, being skin. Amounts vary by brand and recipe, so always check the label of the exact product.
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