Grapefruit
Grapefruit contains moderate levels of Histamine and Tyramine. It has low levels of Sucrose and FODMAPs. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)Moderate
this fruit holds little histamine itself but is a histamine liberator, prompting the body to release its own histamine even when perfectly fresh. Sensitive people often react to that released histamine whatever the freshness.
- TyramineModerate
This is a weak entry and worth saying so: chocolate, cocoa, nuts, citrus and coffee appear on legacy MAOI lists, but modern reviews found their tyramine too low to matter at normal portions — chocolate's effect, if any, is attributed to phenylethylamine rather than tyramine. They were dropped from the strict list decades ago. Test rather than avoid on principle. Sources: Gardner et al., J Clin Psychiatry 1996 (review that narrowed the MAOI diet); McCabe-Sellers et al., J Food Compos Anal 2006.
- SucroseLow
- FODMAPsLow
- SalicylateNone
- LactoseNone
- OligosaccharidesNone
- SorbitolNone
- FructoseNone
- NickelNone
- OxalatesNone
- GlutenNone
Intolerance levels are based on our documented scientific sources. See sources →
React to Histamine (+liberators / DAO inhibitors)? Check these too
More in Fruits
- Acorn squash→
- Apple→
- Apricot→
- Apricot canned→
- Aubergine→
- Avocado→
- Baby marrow→
- Banana→
- Bell pepper→
- Bird's eye chili→
- Blackberry→
- Blackcurrant→
Frequently asked questions
Which intolerances does grapefruit affect?
grapefruit is notable for Histamine, Tyramine, Sucrose and FODMAPs.
Does grapefruit contain Histamine?
grapefruit contains moderate levels of Histamine. this fruit holds little histamine itself but is a histamine liberator, prompting the body to release its own histamine even when perfectly fresh. Sensitive people often react to that released histamine whatever the freshness.
Does grapefruit contain Tyramine?
grapefruit contains moderate levels of Tyramine. This is a weak entry and worth saying so: chocolate, cocoa, nuts, citrus and coffee appear on legacy MAOI lists, but modern reviews found their tyramine too low to matter at normal portions — chocolate's effect, if any, is attributed to phenylethylamine rather than tyramine. They were dropped from the strict list decades ago. Test rather than avoid on principle. Sources: Gardner et al., J Clin Psychiatry 1996 (review that narrowed the MAOI diet); McCabe-Sellers et al., J Food Compos Anal 2006.
Does grapefruit contain Sucrose?
grapefruit contains only low levels of Sucrose.
Does grapefruit contain FODMAPs?
grapefruit contains only low levels of FODMAPs. Amounts vary by brand and recipe, so always check the label of the exact product.