Tartrazine

Tartrazine is notable for histamine and salicylate. Clear on tyramine, sucrose, FODMAPs, lactose, oligosaccharides, sorbitol, fructose, nickel, oxalates and gluten.

Yes — tartrazine is high in histamine. Tartrazine (E102) is the most tested colour on this list, and the testing is the reason to be careful with it in both directions: open observation suggests many reactions, double-blind challenge confirms far fewer. It contains no histamine, and the liberator classification it carries comes from the elimination protocols rather than from a demonstrated release. It is one of the five colours here that must carry the EU warning about activity and attention in children. The Swiss list rates it 3 of 3 and marks it L, its letter for liberators of mast cell mediators — a presumed reason rather than a measurement.

Yes — tartrazine is high in salicylate. Tartrazine is the most documented azo dye in salicylate and aspirin sensitivity — the cross-reaction has been described for decades. It colours soft drinks, sweets and sauces yellow. It is also one of the six colours of Annex V of the additives regulation, which must carry the children's attention warning on the label - a different endpoint from this axis: attention, not salicylate. Amounts vary by brand and recipe, so always check the label of the exact product.