Sulfite

Other names Sulfites, Sulphites
Sulfite: high in histamine; low in tyramine. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)High
Sulfites are on this axis for a reason worth stating precisely, because it is not the one usually given: they are not documented as inhibitors of DAO, the enzyme that clears histamine. Sulfite intolerance is its own condition, and it presents so much like histamine intolerance - and rides in the same foods, wine and dried fruit above all - that the two are eliminated together and routinely confused. The label helps here as almost nowhere else: EU law requires a sulphite declaration above 10 mg/kg. One number is worth carrying over from the additive side: when EFSA re-evaluated the sulfites in 2016 it kept the group ADI at 0.7 mg SO₂ equivalent per kilo of body weight, made it TEMPORARY for want of data, and estimated exposure above that figure for every population group.
Sources· 4
- Comas-Baste et al., Biomolecules 10:1181 (2020)
- Maintz & Novak, Am J Clin Nutr 2007
- Reg. (EU) No 1169/2011 Annex II for the 10 mg/kg declaration
- EFSA (2016), re-evaluation of sulfur dioxide and the sulfites, EFSA Journal 14(4):4438
- TyramineLow
Sulfite is a preservative and antioxidant, and it contains no tyramine. It sits higher on the histamine axis than here, which is not a contradiction: that axis counts liberators - things that make the body release its own histamine - while this one counts content only. There is no tyramine liberator, because the body stores none to release.
- FODMAPsNone
- LactoseFODMAPsNone
- GlutenNone
- FructoseFODMAPsNone
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- SucroseNone
- SalicylateNone
- NickelNone
- OxalatesNone
Intolerance levels are based on our documented scientific sources. See sources →
React to Histamine (+liberators / DAO inhibitors)? Check these too
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Frequently asked questions
Which intolerances does Sulfite affect?
Sulfite is notable for histamine and tyramine. Clear on FODMAPs, lactose, gluten, fructose, oligosaccharides, sorbitol, sucrose, salicylate, nickel and oxalates.
Does Sulfite contain histamine?
Yes — Sulfite is high in histamine. Sulfites are on this axis for a reason worth stating precisely, because it is not the one usually given: they are not documented as inhibitors of DAO, the enzyme that clears histamine. Sulfite intolerance is its own condition, and it presents so much like histamine intolerance - and rides in the same foods, wine and dried fruit above all - that the two are eliminated together and routinely confused. The label helps here as almost nowhere else: EU law requires a sulphite declaration above 10 mg/kg. One number is worth carrying over from the additive side: when EFSA re-evaluated the sulfites in 2016 it kept the group ADI at 0.7 mg SO₂ equivalent per kilo of body weight, made it TEMPORARY for want of data, and estimated exposure above that figure for every population group.
Does Sulfite contain tyramine?
Sulfite contains only low levels of tyramine. Sulfite is a preservative and antioxidant, and it contains no tyramine. It sits higher on the histamine axis than here, which is not a contradiction: that axis counts liberators - things that make the body release its own histamine - while this one counts content only. There is no tyramine liberator, because the body stores none to release. Amounts vary by brand and recipe, so always check the label of the exact product.
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