Orange yellow S

Orange yellow S is notable for histamine and salicylate. Clear on tyramine, sucrose, FODMAPs, lactose, oligosaccharides, sorbitol, fructose, nickel, oxalates and gluten.

Yes — orange yellow S is high in histamine. Sunset yellow (E110) is the orange of soft drinks, sweets and packet desserts, and it holds no histamine itself - the elimination protocols class it as a liberator, a grouping rather than a demonstrated release. It is one of the six colours of the Southampton study, so a product containing it must carry the EU warning about children's activity and attention - which makes it findable on a label without knowing the E number. The Swiss list rates it 3 of 3 and marks it L, its letter for liberators of mast cell mediators — a presumed reason rather than a measurement.

Yes — orange yellow S is high in salicylate. An azo dye from the same family as tartrazine, and a recognised cross-reactor in salicylate sensitivity. Often used alongside it to shade oranges and yellows. It is also one of the six colours of Annex V of the additives regulation, which must carry the children's attention warning on the label - a different endpoint from this axis: attention, not salicylate. Amounts vary by brand and recipe, so always check the label of the exact product.