Octyl gallate

Other names octyl 3,4,5-trihydroxybenzoate, E311
Octyl gallate: high in histamine and salicylate. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)High
Octyl gallate (E311) has a longer chain than propyl gallate, which makes it dissolve in fat instead of water - so it goes into the oils and the fatty spreads. Same family, same reasoning, and the same thin evidence base. None of them carries histamine. The antioxidants are on this page because the pseudoallergen elimination protocols remove them as a family, and the reactions reported are pseudoallergic rather than amine-mediated.
Sources· 2
- Zuberbier et al., EAACI/GA2LEN urticaria guideline
- EFSA re-evaluations of BHA (2011) and BHT (2012)
- SalicylateHigh
The same phenolic antioxidant family as propyl gallate, with a longer chain that suits fattier products. The phenolic structure behind the salicylate cross-reaction is unchanged.
Sources· 1
- Baenkler H-W., Dtsch Arztebl Int 105:8 (2008) 137-142, salicylate intolerance - mechanism, clinical spectrum, diagnosis and treatment
- TyramineNone
- SucroseNone
- FODMAPsNone
- LactoseFODMAPsNone
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- FructoseFODMAPsNone
- NickelNone
- OxalatesNone
- GlutenNo
Intolerance levels are based on our documented scientific sources. See sources →
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Frequently asked questions
Which intolerances does octyl gallate affect?
Octyl gallate is notable for histamine and salicylate. Clear on tyramine, sucrose, FODMAPs, lactose, oligosaccharides, sorbitol, fructose, nickel, oxalates and gluten.
Does octyl gallate contain histamine?
Yes — octyl gallate is high in histamine. Octyl gallate (E311) has a longer chain than propyl gallate, which makes it dissolve in fat instead of water - so it goes into the oils and the fatty spreads. Same family, same reasoning, and the same thin evidence base. None of them carries histamine. The antioxidants are on this page because the pseudoallergen elimination protocols remove them as a family, and the reactions reported are pseudoallergic rather than amine-mediated.
Does octyl gallate contain salicylate?
Yes — octyl gallate is high in salicylate. The same phenolic antioxidant family as propyl gallate, with a longer chain that suits fattier products. The phenolic structure behind the salicylate cross-reaction is unchanged. Amounts vary by brand and recipe, so always check the label of the exact product.
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