Monopotassium glutamate
Other names E622
Monopotassium glutamate: moderate in histamine. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)Moderate
Monopotassium glutamate (E622) is MSG with potassium instead of sodium, used in reduced-sodium seasonings. Same molecule doing the same job, same absence of an established histamine mechanism - and the same reason it stays on the list, which is the company it keeps rather than what it does. EFSA set the first ADI for these additives at 30 mg per kilo of body weight a day, then found exposure above it — and above DOSES ASSOCIATED WITH ADVERSE EFFECTS IN HUMANS — for some population groups. That answers a different question from the blinded challenge: habitual intake, not a meal.
Sources· 3
- Geha et al., J Nutr 2000 (multicentre DBPC MSG trial)
- EFSA re-evaluation of glutamates, 2017
- EFSA Panel on Food Additives (2017), re-evaluation of glutamic acid (E 620) and the glutamates (E 621-E 625) as food additives
- TyramineNone
- SalicylateNone
- SucroseNone
- FODMAPsNone
- LactoseFODMAPsNone
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- FructoseFODMAPsNone
- NickelNone
- OxalatesNone
- GlutenNo
Intolerance levels are based on our documented scientific sources. See sources →
React to Histamine (+liberators / DAO inhibitors)? Check these too
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Frequently asked questions
Which intolerances does monopotassium glutamate affect?
Monopotassium glutamate is notable for histamine. Clear on tyramine, salicylate, sucrose, FODMAPs, lactose, oligosaccharides, sorbitol, fructose, nickel, oxalates and gluten.
Does monopotassium glutamate contain histamine?
Monopotassium glutamate contains moderate levels of histamine. Monopotassium glutamate (E622) is MSG with potassium instead of sodium, used in reduced-sodium seasonings. Same molecule doing the same job, same absence of an established histamine mechanism - and the same reason it stays on the list, which is the company it keeps rather than what it does. EFSA set the first ADI for these additives at 30 mg per kilo of body weight a day, then found exposure above it — and above DOSES ASSOCIATED WITH ADVERSE EFFECTS IN HUMANS — for some population groups. That answers a different question from the blinded challenge: habitual intake, not a meal. Amounts vary by brand and recipe, so always check the label of the exact product.
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