Magnesium diglutamate
Other names E625
Magnesium diglutamate: moderate in histamine. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)Moderate
Magnesium diglutamate (E625) completes the set of glutamate salts, and it is the rarest of them. Which cation is attached changes the solubility and the nutrition panel; it changes nothing about the glutamate, and glutamate is not a liberator. EFSA set the first ADI for these additives at 30 mg per kilo of body weight a day, then found exposure above it — and above DOSES ASSOCIATED WITH ADVERSE EFFECTS IN HUMANS — for some population groups. That answers a different question from the blinded challenge: habitual intake, not a meal.
Sources· 3
- Geha et al., J Nutr 2000 (multicentre DBPC MSG trial)
- EFSA re-evaluation of glutamates, 2017
- EFSA Panel on Food Additives (2017), re-evaluation of glutamic acid (E 620) and the glutamates (E 621-E 625) as food additives
- TyramineNone
- SalicylateNone
- SucroseNone
- FODMAPsNone
- LactoseFODMAPsNone
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- FructoseFODMAPsNone
- NickelNone
- OxalatesNone
- GlutenNo
Intolerance levels are based on our documented scientific sources. See sources →
React to Histamine (+liberators / DAO inhibitors)? Check these too
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Frequently asked questions
Which intolerances does magnesium diglutamate affect?
Magnesium diglutamate is notable for histamine. Clear on tyramine, salicylate, sucrose, FODMAPs, lactose, oligosaccharides, sorbitol, fructose, nickel, oxalates and gluten.
Does magnesium diglutamate contain histamine?
Magnesium diglutamate contains moderate levels of histamine. Magnesium diglutamate (E625) completes the set of glutamate salts, and it is the rarest of them. Which cation is attached changes the solubility and the nutrition panel; it changes nothing about the glutamate, and glutamate is not a liberator. EFSA set the first ADI for these additives at 30 mg per kilo of body weight a day, then found exposure above it — and above DOSES ASSOCIATED WITH ADVERSE EFFECTS IN HUMANS — for some population groups. That answers a different question from the blinded challenge: habitual intake, not a meal. Amounts vary by brand and recipe, so always check the label of the exact product.
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