Caffeine
Other names 1,3,7-Trimethylxanthine, Guaranine
Caffeine: moderate in histamine. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)Moderate
Caffeine holds no histamine. It is flagged because it is widely said to slow DAO, and that claim is worth being honest about: it appears in every food list on this subject and in very little else - reliable studies supporting it are hard to locate. It is on the axis because the lists put it there, not because a mechanism has been shown.
Sources· 2
- Maintz & Novak, Am J Clin Nutr 2007
- Comas-Baste et al., Biomolecules 10:1181 (2020)
- FODMAPsNone
- LactoseFODMAPsNone
- GlutenNo
- FructoseFODMAPsNone
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- SucroseNone
- TyramineNone
- SalicylateNone
- NickelNone
- OxalatesNone
Intolerance levels are based on our documented scientific sources. See sources →
React to Histamine (+liberators / DAO inhibitors)? Check these too
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Frequently asked questions
Which intolerances does Caffeine affect?
Caffeine is notable for histamine. Clear on FODMAPs, lactose, gluten, fructose, oligosaccharides, sorbitol, sucrose, tyramine, salicylate, nickel and oxalates.
Does Caffeine contain histamine?
Caffeine contains moderate levels of histamine. Caffeine holds no histamine. It is flagged because it is widely said to slow DAO, and that claim is worth being honest about: it appears in every food list on this subject and in very little else - reliable studies supporting it are hard to locate. It is on the axis because the lists put it there, not because a mechanism has been shown. Amounts vary by brand and recipe, so always check the label of the exact product.
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