Butylated hydroxyanisole

Other names BHA, E320
Butylated hydroxyanisole: high in histamine; moderate in salicylate and nickel. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)High
BHA (E320) is the phenolic antioxidant used in fats, chewing gum and instant potato, and it appears in pseudoallergen-free diets as a possible liberator on weak, largely observational evidence. Worth knowing rather than avoiding on principle - and worth knowing that it is the most-studied of the three, which is why it carries the higher flag. The Swiss list rates it 2 of 3 and marks it L, its letter for liberators of mast cell mediators — a presumed reason rather than a measurement.
Sources· 3
- Zuberbier et al., EAACI/GA2LEN urticaria guideline
- EFSA re-evaluations of BHA (2011) and BHT (2012)
- SIGHI — Swiss Interest Group Histamine Intolerance, food-compatibility list (2024-08-29), for the L classification and the compatibility rating
- SalicylateModerate
BHA is a phenolic antioxidant added to fats to stop them going rancid, and the phenolic ring is why salicylate-sensitive people react. It does not contain salicylate.
Sources· 1
- Baenkler H-W., Dtsch Arztebl Int 105:8 (2008) 137-142, salicylate intolerance - mechanism, clinical spectrum, diagnosis and treatment
- NickelModerate
Butylated hydroxyanisole is a synthetic antioxidant for fats. Nothing in the molecule contains nickel, but nickel is the workhorse catalyst of industrial organic synthesis, and a trace of the catalyst survives into the product. For this additive there is no legal nickel ceiling at all.
Sources· 1
- Regulation (EU) No 231/2012, purity criteria for food additives
- FODMAPsNone
- LactoseFODMAPsNone
- GlutenNo
- FructoseFODMAPsNone
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- SucroseNone
- TyramineNone
- OxalatesNone
Intolerance levels are based on our documented scientific sources. See sources →
React to Histamine (+liberators / DAO inhibitors)? Check these too
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Frequently asked questions
Which intolerances does Butylated hydroxyanisole affect?
Butylated hydroxyanisole is notable for histamine, salicylate and nickel. Clear on FODMAPs, lactose, gluten, fructose, oligosaccharides, sorbitol, sucrose, tyramine and oxalates.
Does Butylated hydroxyanisole contain histamine?
Yes — Butylated hydroxyanisole is high in histamine. BHA (E320) is the phenolic antioxidant used in fats, chewing gum and instant potato, and it appears in pseudoallergen-free diets as a possible liberator on weak, largely observational evidence. Worth knowing rather than avoiding on principle - and worth knowing that it is the most-studied of the three, which is why it carries the higher flag. The Swiss list rates it 2 of 3 and marks it L, its letter for liberators of mast cell mediators — a presumed reason rather than a measurement.
Does Butylated hydroxyanisole contain salicylate?
Butylated hydroxyanisole contains moderate levels of salicylate. BHA is a phenolic antioxidant added to fats to stop them going rancid, and the phenolic ring is why salicylate-sensitive people react. It does not contain salicylate.
Does Butylated hydroxyanisole contain nickel?
Butylated hydroxyanisole contains moderate levels of nickel. Butylated hydroxyanisole is a synthetic antioxidant for fats. Nothing in the molecule contains nickel, but nickel is the workhorse catalyst of industrial organic synthesis, and a trace of the catalyst survives into the product. For this additive there is no legal nickel ceiling at all. Amounts vary by brand and recipe, so always check the label of the exact product.
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