Grana Padano

Other names Grana Padano cheese, Grana Padano cheese from cow's milk
Grana Padano: moderate in histamine and tyramine. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)Moderate
Grana Padano is parmigiano's near neighbour and sits below it for a reason the specification gives: it permits lysozyme, up to 2.5 g per 100 kg, added to stop unwanted fermentation - and suppressing bacteria suppresses the amines they make. Its minimum ageing, 9 months against parmigiano's 12, is the smaller half of the difference. Neither fact is a histamine measurement; both are why two cheeses that look alike are not the same object.
Sources· 2
- Parmigiano Reggiano and Grana Padano DOP specifications, for the minimum ageing and the lysozyme provision
- EFSA Panel on Biological Hazards, EFSA Journal 2011, and McCabe-Sellers et al., J Food Compos Anal 2006, for the amines
- TyramineModerate
Grana Padano is one of only two cheeses in this group that is not high, and its specification explains why better than its age does. Its minimum ageing is 9 months against parmigiano's 12 - a small gap - but it also permits LYSOZYME, up to 2.5 g per 100 kg, added precisely to stop unwanted fermentation. Parmigiano allows no additive at all. Suppressing bacteria is what suppresses tyramine.
Sources· 2
- Parmigiano Reggiano and Grana Padano DOP specifications, for the minimum ageing and the lysozyme provision
- EFSA Panel on Biological Hazards, EFSA Journal 2011, and McCabe-Sellers et al., J Food Compos Anal 2006, for the amines
- SalicylateNone
- SucroseNone
- FODMAPsNone
- LactoseFODMAPsNone
Grana Padano is one of the six cheeses measured with neither lactose nor galactose detectable, which is why it appears on galactosaemia diets alongside parmigiano. Nine months is its minimum ripening - shorter than parmesan's, and still long enough for the cultures to finish the sugar.
Sources· 2
- Portnoi PA & MacDonald A, J Hum Nutr Diet 22 (2009), 400-408, 109 samples of 12 cheese types analysed for the UK Galactosaemia Support Group
- USDA FoodData Central
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- FructoseFODMAPsNone
- NickelNone
- OxalatesNone
- GlutenNo
Intolerance levels are based on our documented scientific sources. See sources →
React to Histamine (+liberators / DAO inhibitors)? Check these too
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Frequently asked questions
Which intolerances does Grana Padano affect?
Grana Padano is notable for histamine and tyramine. Clear on salicylate, sucrose, FODMAPs, lactose, oligosaccharides, sorbitol, fructose, nickel, oxalates and gluten.
Does Grana Padano contain histamine?
Grana Padano contains moderate levels of histamine. Grana Padano is parmigiano's near neighbour and sits below it for a reason the specification gives: it permits lysozyme, up to 2.5 g per 100 kg, added to stop unwanted fermentation - and suppressing bacteria suppresses the amines they make. Its minimum ageing, 9 months against parmigiano's 12, is the smaller half of the difference. Neither fact is a histamine measurement; both are why two cheeses that look alike are not the same object.
Does Grana Padano contain tyramine?
Grana Padano contains moderate levels of tyramine. Grana Padano is one of only two cheeses in this group that is not high, and its specification explains why better than its age does. Its minimum ageing is 9 months against parmigiano's 12 - a small gap - but it also permits LYSOZYME, up to 2.5 g per 100 kg, added precisely to stop unwanted fermentation. Parmigiano allows no additive at all. Suppressing bacteria is what suppresses tyramine. Amounts vary by brand and recipe, so always check the label of the exact product.
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