Italian hard cheese Grana Padano
Italian hard cheese Grana Padano contains moderate levels of Histamine and Tyramine. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)Moderate
hard, long-aged cheeses are among the highest-histamine foods, and the longer the ageing the more histamine they hold. Young, fresh, unaged cheeses contain far less histamine.
- TyramineModerate
Aged cheese is the reference tyramine food — the 'cheese effect' is named after it. Bacteria break the milk protein down over months and decarboxylate its tyrosine, so tyramine tracks ageing almost linearly: a mature cheddar or a blue can exceed 100 mg/kg while a fresh cheese sits near zero. Cooking does not destroy it, and it keeps rising in the fridge after opening. If you take an MAOI antidepressant this is the single most important food to avoid — a large portion can trigger a hypertensive crisis. Sources: EFSA Panel on Biological Hazards, Scientific Opinion on tyramine and histamine in fermented foods, EFSA Journal 2011; McCabe-Sellers et al., J Food Compos Anal 2006; Gardner et al., J Clin Psychiatry 1996.
- SalicylateNone
- SucroseNone
- FODMAPsNone
- LactoseNone
- OligosaccharidesNone
- SorbitolNone
- FructoseNone
- NickelNone
- OxalatesNone
- GlutenNo
Intolerance levels are based on our documented scientific sources. See sources →
React to Histamine (+liberators / DAO inhibitors)? Check these too
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- Buttermilk→
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- Casein→
- Cheddar→
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Frequently asked questions
Which intolerances does Italian hard cheese Grana Padano affect?
Italian hard cheese Grana Padano is notable for Histamine and Tyramine.
Does Italian hard cheese Grana Padano contain Histamine?
Italian hard cheese Grana Padano contains moderate levels of Histamine. hard, long-aged cheeses are among the highest-histamine foods, and the longer the ageing the more histamine they hold. Young, fresh, unaged cheeses contain far less histamine.
Does Italian hard cheese Grana Padano contain Tyramine?
Italian hard cheese Grana Padano contains moderate levels of Tyramine. Aged cheese is the reference tyramine food — the 'cheese effect' is named after it. Bacteria break the milk protein down over months and decarboxylate its tyrosine, so tyramine tracks ageing almost linearly: a mature cheddar or a blue can exceed 100 mg/kg while a fresh cheese sits near zero. Cooking does not destroy it, and it keeps rising in the fridge after opening. If you take an MAOI antidepressant this is the single most important food to avoid — a large portion can trigger a hypertensive crisis. Sources: EFSA Panel on Biological Hazards, Scientific Opinion on tyramine and histamine in fermented foods, EFSA Journal 2011; McCabe-Sellers et al., J Food Compos Anal 2006; Gardner et al., J Clin Psychiatry 1996. Amounts vary by brand and recipe, so always check the label of the exact product.