Soy sauce

Other names soya sauce, Soy sauces
Soy sauce: high in tyramine and gluten; moderate in histamine, salicylate and nickel. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- TyramineHigh
Soy sauce is brewed for months with mould, yeast and lactic bacteria in turn, each stage breaking the soy protein down further - which is exactly what produces tyramine. It is poured in small volumes and it is very concentrated, so the volume is the only thing keeping the dose down.
Sources· 2
- EFSA Journal 2011 (tyramine and histamine in fermented foods)
- McCabe-Sellers et al., J Food Compos Anal 2006
- GlutenContains
Standard soy sauce is brewed with wheat and contains gluten. Choose tamari labelled gluten-free as a safe alternative.
- Histamine (+liberators / DAO inhibitors)Moderate
Soy sauce is brewed for months with mould, yeast and lactic bacteria in turn, and each of those stages breaks protein down further - which is exactly what produces amines. It is used by the spoonful, which is the only thing keeping it where it is rather than higher. There is no low-histamine soy sauce. Gardner's narrowed MAOI diet names it, and names it as a category — "soy sauce and soy bean condiments" — which covers miso, tamari and the rest of the shelf rather than one bottle.
Sources· 3
- Comas-Baste et al., Biomolecules 2020
- McCabe-Sellers et al., J Food Compos Anal 2006
- Gardner D.M. et al., J Clin Psychiatry 57 (1996) 99-104, the review that narrowed the MAOI diet
- SalicylateModerate
The salicylate of a soy sauce comes from the long ferment rather than from any added spice, and no measurement separates soy sauce from tamari here - the two carry the same level for that reason. It is poured by the spoonful, so the portion stays modest unless the sauce is the dish rather than the seasoning.
Sources· 1
- Duthie G.G. & Wood A.D., Food Funct 2 (2011) 515-520, natural salicylates in foods
- NickelModerate
Soy sauce is the soya bean fermented and poured, and the bean is a nickel accumulator - legumes take nickel up as the cofactor of urease. The brine dilutes it and the spoonful limits it, which is what keeps this a step below the bean itself. Tamari answers the same way: the wheat is the only difference between the two, and wheat is not where the nickel is.
Sources· 1
- Noel L et al., Food Chemistry 132 (2012) 1502-1513, second French Total Diet Study, nickel among nine trace elements
- SucroseNone
- FODMAPsNone
- LactoseFODMAPsNone
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- FructoseFODMAPsNone
- OxalatesNone
Intolerance levels are based on our documented scientific sources. See sources →
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Frequently asked questions
Which intolerances does soy sauce affect?
Soy sauce is notable for tyramine, gluten, histamine, salicylate and nickel. Clear on sucrose, FODMAPs, lactose, oligosaccharides, sorbitol, fructose and oxalates.
Does soy sauce contain tyramine?
Yes — soy sauce is high in tyramine. Soy sauce is brewed for months with mould, yeast and lactic bacteria in turn, each stage breaking the soy protein down further - which is exactly what produces tyramine. It is poured in small volumes and it is very concentrated, so the volume is the only thing keeping the dose down.
Does soy sauce contain gluten?
Yes — soy sauce is high in gluten. Standard soy sauce is brewed with wheat and contains gluten. Choose tamari labelled gluten-free as a safe alternative.
Does soy sauce contain histamine?
Soy sauce contains moderate levels of histamine. Soy sauce is brewed for months with mould, yeast and lactic bacteria in turn, and each of those stages breaks protein down further - which is exactly what produces amines. It is used by the spoonful, which is the only thing keeping it where it is rather than higher. There is no low-histamine soy sauce. Gardner's narrowed MAOI diet names it, and names it as a category — "soy sauce and soy bean condiments" — which covers miso, tamari and the rest of the shelf rather than one bottle.
Does soy sauce contain salicylate?
Soy sauce contains moderate levels of salicylate. The salicylate of a soy sauce comes from the long ferment rather than from any added spice, and no measurement separates soy sauce from tamari here - the two carry the same level for that reason. It is poured by the spoonful, so the portion stays modest unless the sauce is the dish rather than the seasoning. Amounts vary by brand and recipe, so always check the label of the exact product.
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