Vodka

Vodka: moderate in histamine and salicylate; low in gluten. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- Histamine (+liberators / DAO inhibitors)Moderate
Vodka is distilled to the highest purity of any spirit and filtered afterwards, so it carries essentially nothing but ethanol and water - no histamine survives a still. The ethanol is the whole problem: it blocks DAO, so the vodka is not the source, it is the handbrake on everything else in the meal.
Sources· 3
- Maintz & Novak, Am J Clin Nutr 2007
- Comas-Baste et al., Biomolecules 2020
- EFSA (2016), re-evaluation of sulfur dioxide and the sulfites, EFSA Journal 14(4):4438
- SalicylateModerate
Distillation leaves very little salicylate behind, so vodka is here almost entirely for alcohol's own effect — increased gut permeability and slower salicylate clearance. Neither study publishes a value for this particular drink.
Sources· 2
- Duthie G.G. & Wood A.D., Food Funct 2 (2011) 515-520, natural salicylates in foods
- Scotter M.J. et al., Food Chem 105 (2007) 273-279, and Venema D. et al., J Agric Food Chem 44 (1996) 1762-1767
- GlutenPossible
Vodka is gluten-free even when it is made from wheat, and the reason is physical: gluten is a protein, protein does not evaporate, and only the vapour leaves a still. The grain on the bottle tells you about the flavour, not about the gluten. The law says it in one line, and the line is worth quoting: Annex II exempts 'cereals used for making alcoholic distillates including ethyl alcohol of agricultural origin' from the gluten declaration. An exemption is a judgement about the process, not a measurement of the bottle - which is why what is added AFTER distillation is still the open question.
Sources· 5
- Coeliac UK — gluten free diet guidance: “All spirits are distilled during the manufacturing process and this process removes any trace of gluten”
- beer, lagers, stouts and ales not suitable
- gluten free beer at or below 20 ppm
- barley malt vinegar to be both tested and labelled gluten free
- Regulation (EU) No 1169/2011, Annex II
- TyramineNone
- SucroseNone
- FODMAPsNone
- LactoseFODMAPsNone
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- FructoseFODMAPsNone
- NickelNone
- OxalatesNone
Intolerance levels are based on our documented scientific sources. See sources →
React to Histamine (+liberators / DAO inhibitors)? Check these too
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Frequently asked questions
Which intolerances does vodka affect?
Vodka is notable for histamine, salicylate and gluten. Clear on tyramine, sucrose, FODMAPs, lactose, oligosaccharides, sorbitol, fructose, nickel and oxalates.
Does vodka contain histamine?
Vodka contains moderate levels of histamine. Vodka is distilled to the highest purity of any spirit and filtered afterwards, so it carries essentially nothing but ethanol and water - no histamine survives a still. The ethanol is the whole problem: it blocks DAO, so the vodka is not the source, it is the handbrake on everything else in the meal.
Does vodka contain salicylate?
Vodka contains moderate levels of salicylate. Distillation leaves very little salicylate behind, so vodka is here almost entirely for alcohol's own effect — increased gut permeability and slower salicylate clearance. Neither study publishes a value for this particular drink.
Does vodka contain gluten?
Vodka contains only low levels of gluten. Vodka is gluten-free even when it is made from wheat, and the reason is physical: gluten is a protein, protein does not evaporate, and only the vapour leaves a still. The grain on the bottle tells you about the flavour, not about the gluten. The law says it in one line, and the line is worth quoting: Annex II exempts 'cereals used for making alcoholic distillates including ethyl alcohol of agricultural origin' from the gluten declaration. An exemption is a judgement about the process, not a measurement of the bottle - which is why what is added AFTER distillation is still the open question. Amounts vary by brand and recipe, so always check the label of the exact product.
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