Oyster

Oyster: high in nickel; low in histamine. If you're sensitive to any of these, check it against your profile before eating.
Intolerances
- NickelHigh
Oysters filter enormous volumes of seawater and keep what they filter, trace metals included. That is the same mechanism that makes them high in zinc, working on a metal nobody wants. The second French Total Diet Study ranks the food groups for nickel rather than valuing them, and tofu heads that ranking.
Sources· 1
- Noel L et al., Food Chemistry 132 (2012) 1502-1513, second French Total Diet Study, nickel among nine trace elements
- Histamine (+liberators / DAO inhibitors)Low
Oysters are low in histamine when alive and cold, which is how they are sold - but shellfish are also classic histamine liberators, releasing the body's own stores without carrying much themselves. That is a different mechanism and this level does not cover it. The Swiss list rates it 2 of 3 under “oysters” and marks it H! for rapid histamine formation and L for liberators of mast cell mediators. The letters are a presumed reason, not a measurement.
Sources· 2
- SIGHI — Swiss Interest Group Histamine Intolerance, food-compatibility list (2024-08-29), for the entry, its rating and its letters
- Piersanti A. et al., Food Chem 153 (2014) 437-443, four years of official-control histamine results on fish products
- FODMAPsNone
- LactoseFODMAPsNone
- GlutenNone
- FructoseFODMAPsNone
- OligosaccharidesFODMAPsNone
- SorbitolFODMAPsNone
- SucroseNone
- TyramineNone
- SalicylateNone
- OxalatesNone
Intolerance levels are based on our documented scientific sources. See sources →
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Frequently asked questions
Which intolerances does oyster affect?
Oyster is notable for nickel and histamine. Clear on FODMAPs, lactose, gluten, fructose, oligosaccharides, sorbitol, sucrose, tyramine, salicylate and oxalates.
Does oyster contain nickel?
Yes — oyster is high in nickel. Oysters filter enormous volumes of seawater and keep what they filter, trace metals included. That is the same mechanism that makes them high in zinc, working on a metal nobody wants. The second French Total Diet Study ranks the food groups for nickel rather than valuing them, and tofu heads that ranking.
Does oyster contain histamine?
Oyster contains only low levels of histamine. Oysters are low in histamine when alive and cold, which is how they are sold - but shellfish are also classic histamine liberators, releasing the body's own stores without carrying much themselves. That is a different mechanism and this level does not cover it. The Swiss list rates it 2 of 3 under “oysters” and marks it H! for rapid histamine formation and L for liberators of mast cell mediators. The letters are a presumed reason, not a measurement. Amounts vary by brand and recipe, so always check the label of the exact product.
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